Map ctrl+alt+esc keybinding to start xkill ccommand in kde's systemsettings.
Will probably not help if WIREHEAD is running Compiz and Emerald. But a couple of yeas ago I used to define an alternative shortcut from within Compiz.
That's because compiz grabs the ctrl + alt + esc shortcut for something else.
Hmmm. Wasn't that what I was trying to say earlier?
You can use kwin, kde's native and integrated window manager which btw also has a nice collection of effects. Or you can search ccsm and change or delete the keyboard shortcut so kde can use it again.
The interesting thing is that if you use
KWin and have the shortcut set up in System Settings you don't need the
xkill package. Ctrl+Alt+Esc will work anyway.
But if you
have installed the package you'll find
XKill in the K-menu under "More Applications"->"Monitoring", and you could simply drag the entry to the panel (with widgets unlocked). Then you could start it by just clicking the icon.
(Which you might want to change first. You may find the default icon incredibly ugly.)
I'd go for the first solution because of the integration but maybe you have a good reason not to use kwin.
Of course Compiz is still more versatile even if slightly less well integrated. That's why some of us are looking forward to KDE 4.6....

btw, e17 took care of this much better, i just have to right-click the close button to kill the window or kill it from the window menu.