I'm glad I found this post. I am trying the LXDE live CD and encountered this problem, but I thought it was strictly related to my preference for double clicking. I almost never use icon view, just a detailed listing when that's available.
I did not encounter any problems when using single clicking, just double clicking. My workaround was to right click and 'Open in new Tab' which gave me a new tabbed window that worked for another double click after which I would have to do it again. I was beginning to have a lot
I never suspected that changing the view would help, but it does, so I now switch to icon view and back, and that clears the problem. But I find myself having to do this constantly, which is not satisfactory at all.
Hopefully this will be cleared up soon.