I'd do it in reverse... at the router so all systems (phones, Nook, PS3, Wii, TiVo, etc.) don't have to be set up individually. I just point them to 192.168.1.1.
Primary: 8.8.4.4
Secondary: 208.67.222.222
Except for my children's PC, where I use OpenDNS 208.67.222.123 and 208.67.220.123 which offers some additional filtering...