Thanks for the link wedgeling, good stuff there. I got quite absorbed in reading various items here
Me too, and I found (in an article wrote by parnote) one thing I wasn't aware about: how editing/transcoding repeatedly an audio file in a lossy format (mp3, ogg etc) will degrade its quality, and how is best to do the editing in a lossless format.
Good stuff indeed 
To recap what dubigrasu is referring to ...
Convert your audio file to a lossless (WAV, AIF, or FLAC)
before you edit and transcode. Then, after you have everything the way you want it, then save the file in one of the compressed formats (mp3, ogg, etc.). Doing your edits and transcoding in this manner will preserve as much quality of your original file as possible.
The article dubigrasu is referring to appeared in the
August, 2009 issue of The NEW PCLinuxOS Magazine. You can also read the HTML version
here.
parnote